Publikationen

2022

• Anker SC, Morgenstern J, Adler J, Brune M, Brings S, Fleming T, Kliemank E, Zorn M, Fischer A, Szendroedi J, Kihm L, Zemva J. Verification of sex- and age-specific reference intervals for 13 serum steroids determined by mass spectrometry: evaluation of an indirect statistical approach.Clin Chem Lab Med. 2022 Dec 20. doi: 10.1515/cclm-2022-0603. Epub ahead of print. PMID: 36537103.
• Alsina-Sanchis E, Mülfarth R, Moll I, Böhn S, Wiedmann L, Jordana-Urriza L, Ziegelbauer T, Zimmer E, Taylor J, De Angelis Rigotti F, Stögbauer A, Giaimo BD, Cerwenka A, Borggrefe T, Fischer A, Rodriguez-Vita J. Endothelial RBPJ Is Essential for the Education of Tumor-Associated Macrophages.Cancer Res. 2022 Dec 2; 82(23):4414-4428. doi: 10.1158/0008-5472.CAN-22-0076. PMID: 36200806.
• Li A, Muenst S, Hoffman J, Starck L, Sarem M, Fischer A, Hutter G, Shastri VP. Mesenchymal-endothelial nexus in breast cancer spheroids induces vasculogenesis and local invasion in a CAM model.Commun Biol. 2022 Nov 27; 5(1):1303. doi: 10.1038/s42003-022-04236-5. PMID: 36435836; PMCID: PMC9701219.
• O'Sullivan ED, Mylonas KJ, Bell R, Carvalho C, Baird DP, Cairns C, Gallagher KM, Campbell R, Docherty M, Laird A, Henderson NC, Chandra T, Kirschner K, Conway B, Dihazi GH, Zeisberg M, Hughes J, Denby L, Dihazi H, Ferenbach DA. Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis.JCI Insight. 2022 Nov 22; 7(22):e154124. doi: 10.1172/jci.insight.154124. PMID: 36509292; PMCID: PMC9746814.
• Bartl M, Dakna M, Schade S, Otte B, Wicke T, Lang E, Starke M, Ebentheuer J, Weber S, Toischer K, Schnelle M, Sixel-Döring F, Trenkwalder C, Mollenhauer B. Blood Markers of Inflammation, Neurodegeneration, and Cardiovascular Risk in Early Parkinson's Disease.Mov Disord. 2022 Oct 20. doi: 10.1002/mds.29257. Epub ahead of print. PMID: 36267007.
• Dierks S, Thiele K, Bohne W, Lugert R, Weig M, Groß U, von Ahsen N, Schanz J, Fischer A, Schnelle M.Comparison and Harmonization of Different Semi-Automated and Automated qRT-PCR Assays in the Assessment of SARS-CoV-2.Viruses. 2022 Oct 12; 14(10):2239. doi: 10.3390/v14102239. PMID: 36298793; PMCID: PMC9610219.
• Eidizadeh A, Schnelle M, Leha A, Edelmann F, Nolte K, Werhahn SM, Binder L, Wachter R. Biomarker profiles in heart failure with preserved vs. reduced ejection fraction: results from the DIAST-CHF study.ESC Heart Fail. 2022 Oct 2. doi: 10.1002/ehf2.14167. Epub ahead of print. PMID: 36184749.
• Eidizadeh A, Papert S, Valk J, Pollok-Kopp B, Goldmann M, Riggert J, Moltrecht R, Legler TJ. Adverse drug reactions following lymphocyte immunotherapy for the treatment of infertility: A retrospective study.J Obstet Gynaecol Res. 2022 Oct; 48(10):2571-2582. doi: 10.1111/jog.15348. Epub 2022 Jul 1. PMID: 35775609.
• Jarausch J, Neuenroth L, Andag R, Leha A, Fischer A, Asif AR, Lenz C, Eidizadeh A.Influence of Shear Stress, Inflammation and BRD4 Inhibition on Human Endothelial Cells: A Holistic Proteomic Approach.Cells. 2022 Sep 30; 11(19):3086. doi: 10.3390/cells11193086. PMID: 36231049; PMCID: PMC9563250.
• Zia A, Aziz M, Popa I, Khan SA, Hamedani AF, Asif AR.Artificial Intelligence-Based Medical Data Mining. J Pers Med. 2022 Aug 24;12(9):1359. doi: 10.3390/jpm12091359. PMID: 36143144; PMCID: PMC9501106.
• Lange T, Backhaus SJ, Beuthner BE, Topci R, Rigorth KR, Kowallick JT, Evertz R, Schnelle M, Ravassa S, Díez J, Toischer K, Seidler T, Puls M, Hasenfuß G, Schuster A. Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study.J Cardiovasc Magn Reson. 2022 Jul 28; 24(1):45. doi: 10.1186/s12968-022-00874-0. PMID: 35897100; PMCID: PMC9331125.
• Kwiatkowski M, Hotze M, Schumacher J, Asif AR, Pittol JMR, Brenig B, Ramljak S, Zischler H, Herlyn H. Protein speciation is likely to increase the chance of proteins to be determined in 2-DE/MS.Electrophoresis. 2022 Jun; 43(11):1203-1214. Doi: 10.1002/elps.202000393. Epub 2022 Apr 18. PMID: 35285965.
• Wolff G, Sakurai M, Mhamane A, Troullinaki M, Maida A, Deligiannis IK, Yin K, Weber P, Morgenstern J, Wieder A, Kwon Y, Sekar R, Zeigerer A, Roden M, Blüher M, Volk N, Poth T, Hackert T, Wiedmann L, De Angelis Rigotti F, Rodriguez-Vita J, Fischer A, Mukthavaram R, Limphong P, Tachikawa K, Karmali P, Payne J, Chivukula P, Ekim-Üstünel B, Martinez-Jimenez CP, Szendrödi J, Nawroth P, Herzig S. Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.Mol Metab. 2022 Jun; 60:101487. doi: 10.1016/j.molmet.2022.101487. Epub 2022 Apr 1. PMID: 35378329; PMCID: PMC9034319.
• Lüders KA, Braunschweig L, Zioła-Frankowska A, Stojek A, Jakkielska D, Wichmann A, Dihazi GH, Streit F, Güsewell SE, Trüe TC, Lüders S, Schlie J, Tsaknakis K, Lorenz HM, Frankowski M, Hell AK. Titanium wear from magnetically controlled growing rods (MCGRs) for the treatment of spinal deformities in children.Sci Rep. 2022 Jun 25; 12(1):10811. doi: 10.1038/s41598-022-15057-1. PMID: 35752736; PMCID: PMC9233686.
• Mohamed BA, Elkenani M, Mobarak S, Marques Rodrigues D, Annamalai K, Schnelle M, Bader M, Hasenfuss G, Toischer K. Hemodynamic stress-induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein.J Cell Mol Med. 2022 Jul 20. doi: 10.1111/jcmm.17468. Epub ahead of print. PMID: 35860864.
• Hartmann N, Preuß L, Mohamed BA, Schnelle M, Renner A, Hasenfuß G, Toischer K. Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation.ESC Heart Fail. 2022 Jun; 9(3):1823-1831. doi: 10.1002/ehf2.13877. Epub 2022 Mar 21. PMID: 35315235; PMCID: PMC9065823.
• Hollstein MM, Münsterkötter L, Schön MP, Bergmann A, Husar TM, Abratis A, Eidizadeh A, Dierks S, Schaffrinski M, Zachmann K, Schmitz A, Holsapple JS, Stanisz-Bogeski H, Schanz J, Fischer A, Groß U, Leha A, Zautner AE, Schnelle M*, Erpenbeck L*. Long-term effects of homologous and heterologous SARS-CoV-2 vaccination on humoral and cellular immune responses.Allergy. 2022 May 14. doi: 10.1111/all.15373. Epub ahead of print. PMID: 35567394.
  • *equally contributed to this work
• Dierks S, Andag R, Gauss F, Budde K, Francke P, Peschka M, Fischer A, Schanz J, Petersmann A.Evaluation of the AFIAS-1 thyroid-stimulating hormone point of care test and comparison with laboratory-based devices.Clin Chem Lab Med. 2022 Apr 25;60(7):1031-1038. doi: 10.1515/cclm-2022-0054. PMID: 35451300.
• Tayyeb A*, Dihazi GH*, Tampe B, Zeisberg M, Tampe D, Hakroush S, Bührig C, Frese J, Serin N, Eltoweissy M, Müller GA, Dihazi H. Calreticulin Shortage Results in Disturbance of Calcium Storage, Mitochondrial Disease, and Kidney Injury.Cells. 2022 Apr 13; 11(8):1329. doi: 10.3390/cells11081329. PMID: 35456008; PMCID: PMC9025518.
  • *equally contributed to this work
• Eidizadeh A, Wiederhold M, Schnelle M, Binder L.Comparison of a novel automated DiaSys procalcitonin immunoassay with four different BRAHMS-partnered immunoassays.Pract Lab Med. 2022 Apr 12;30:e00274. doi: 10.1016/j.plabm.2022.e00274. PMID: 35465623; PMCID: PMC9026940.
• Zechmeister B, Erden T, Kreutzig B, Weber M, Joly P, Erdmann J, Brockmann-Hönig C, Fischer A, Eidizadeh A.Analytical interference of 33 different hemoglobin variants on HbA1c measurements comparing high-performance liquid chromatography with whole blood enzymatic assay: A multi-center study.Clin Chim Acta. 2022 Jun 1;531:145-151. doi: 10.1016/j.cca.2022.03.028. Epub 2022 Apr 1. PMID: 35378091.
• Upmanyu N, Jin J, Emde HV, Ganzella M, Bösche L, Malviya VN, Zhuleku E, Politi AZ, Ninov M, Silbern I, Leutenegger M, Urlaub H, Riedel D, Preobraschenski J, Milosevic I, Hell SW, Jahn R, Sambandan S. Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3.Neuron. 2022 May 4; 110(9):1483-1497.e7. doi: 10.1016/j.neuron.2022.02.008. Epub 2022 Mar 8. PMID: 35263617.
• Hasan SS, Fischer A.Notch Signaling in the Vasculature: Angiogenesis and Angiocrine Functions.Cold Spring Harb Perspect Med. 2022 Jun 6:a041166. doi: 10.1101/cshperspect.a041166. Epub ahead of print. PMID: 35667708.
• Jayavelu AK, Wolf S, Buettner F, Alexe G, Häupl B, Comoglio F, Schneider C, Doebele C, Fuhrmann DC, Wagner S, Donato E, Andresen C, Wilke AC, Zindel A, Jahn D, Splettstoesser B, Plessmann U, Münch S, Abou-El-Ardat K, Makowka P, Acker F, Enssle JC, Cremer A, Schnütgen F, Kurrle N, Chapuy B, Löber J, Hartmann S, Wild PJ, Wittig I, Hübschmann D, Kaderali L, Cox J, Brüne B, Röllig C, Thiede C, Steffen B, Bornhäuser M, Trumpp A, Urlaub H, Stegmaier K, Serve H, Mann M, Oellerich T. The proteogenomic subtypes of acute myeloid leukemia.Cancer Cell. 2022 Mar 14; 40(3):301-317.e12. doi: 10.1016/j.ccell.2022.02.006. Epub 2022 Mar 3. PMID: 35245447.
• Mishto M, Horokhovskyi Y, Cormican JA, Yang X, Lynham S, Urlaub H, Liepe J. Database search engines and target database features impinge upon the identification of post-translationally cis-spliced peptides in HLA class I immunopeptidomes.Proteomics. 2022 May;22(10):e2100226. doi: 10.1002/pmic.202100226. Epub 2022 Mar 3. PMID: 35184383; PMCID: PMC9286349
• Weis EM, Puchalska P, Nelson AB, Taylor J, Moll I, Hasan SS, Dewenter M, Hagenmüller M, Fleming T, Poschet G, Hotz-Wagenblatt A, Backs J, Crawford PA, Fischer A.Ketone body oxidation increases cardiac endothelial cell proliferation.EMBO Mol Med. 2022 Feb 18; e14753. doi: 10.15252/emmm.202114753. Online ahead of print.
• Masetto T, Eidizadeh A, Peter C, Grimmler M. National external quality assessment and direct method comparison reflect crucial deviations of Procalcitonin measurements in Germany. Clin Chim Acta. 2022 Feb 12; 529:67-75. doi: 10.1016/j.cca.2022.02.007. Epub ahead of print. PMID: 35167843.
• Hollstein MM, Münsterkötter L, Schön MP, Bergmann A, Husar TM, Abratis A, Eidizadeh A, Schaffrinski M, Zachmann K, Schmitz A, Holsapple JS, Stanisz-Bogeski H, Schanz J, Fischer A, Groß U, Leha A, Zautner AE, Schnelle M*, Erpenbeck L*. Interdependencies of cellular and humoral immune responses in heterologous and homologous SARS-CoV-2 vaccination. Allergy. 2022 Feb 6. doi: 10.1111/all.15247. Online ahead of print.
  • *equally contributed to this work
• Münsterkötter L, Hollstein MM, Hahn A, Kröger A, Schnelle M, Erpenbeck L, Groß U, Frickmann H, Zautner AE. Comparison of the Anti-SARS-CoV-2 Surrogate Neutralization Assays by TECOmedical and DiaPROPH-Med with Samples from Vaccinated and Infected Individuals. Viruses. 2022 Feb 3;14(2):315. doi: 10.3390/v14020315. PMID: 35215912; PMCID: PMC8877287.
• Chang HF, Schirra C, Ninov M, Hahn U, Ravichandran K, Krause E, Becherer U, Bálint Š, Harkiolaki M, Urlaub H, Valitutti S, Baldari CT, Dustin ML, Jahn R, Rettig J. Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes.Nat Commun. 2022 Feb 24;13(1):1029. doi: 10.1038/s41467-022-28596-y. PMID: 35210420; PMCID: PMC8873490.
• Fang P, Ji Y, Oellerich T, Urlaub H, Pan KT. Strategies for Proteome-Wide Quantification of Glycosylation Macro- and Micro-Heterogeneity.Int J Mol Sci. 2022 Jan 30;23(3):1609. doi: 10.3390/ijms23031609. PMID: 35163546; PMCID: PMC8835892.
• Fichtner A, Bohnenberger H, Elakad O, Richter A, Lenz C, Oing C, Ströbel P, Kueffer S, Nettersheim D, Bremmer F. Proteomic profiling of cisplatin-resistant and cisplatin-sensitive germ cell tumour cell lines using quantitative mass spectrometry.World J Urol. 2022 Feb;40(2):373-383. doi: 10.1007/s00345-022-03936-1. Epub 2022 Jan 27. PMID: 35084545; PMCID: PMC8921118.
• Caldi Gomes L, Galhoz A, Jain G, Roser AE, Maass F, Carboni E, Barski E, Lenz C, Lohmann K, Klein C, Bähr M, Fischer A, Menden MP, Lingor P. Multi-omic landscaping of human midbrains identifies disease-relevant molecular targets and pathways in advanced-stage Parkinson's disease.Clin Transl Med. 2022 Jan;12(1):e692. doi: 10.1002/ctm2.692. PMID: 35090094; PMCID: PMC8797064.

2020

• Bertram K, El Ayoubi L, Dybkov O, Agafonov DE, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Lührmann R (2020) Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome. MOL CELL 80(1): 127-139.e6, doi: 10.1016/j.molcel.2020.09.012
• Blazquez R, Rietkötter E, Wenske B, Wlochowitz D, Sparrer D, Vollmer E, Müller G, Seegerer J, Sun X, Dettmer K, Barrantes-Freer A, Stange L, Utpatel K, Bleckmann A, Treiber H, Bohnenberger H, Lenz C, Schulz M, Reimelt C, Hackl C, Grade M, Büyüktas D, Siam L, Balkenhol M, Stadelmann C, Kube D, Krahn MP, Proescholdt MA, Riemenschneider MJ, Evert M, Oefner PJ, Klein CA, Hanisch UK, Binder C, Pukrop T (2020) LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer. INT J CANCER 146(11): 3170-3183, doi: 10.1002/ijc.32742
• Bobenko A, Duvinage A, Mende M, Holzendorf V, Nolte K, Herrmann-Lingen C, Binder L, Düngen HD, Hasenfuss G, Pieske B, Wachter R, Edelmann F (2020) Outcome assessment using estimation of left ventricular filling pressure in asymptomatic patients at risk for heart failure with preserved ejection fraction. Int J Cardiol Heart Vasc 28: 100525, doi: 10.1016/j.ijcha.2020.100525
• Dihazi GH, Eltoweissy M, Jahn O, Tampe B, Zeisberg M, Wülfrath HS, Müller GA, Dihazi H (2020) The Secretome Analysis of Activated Human Renal Fibroblasts Revealed Beneficial Effect of the Modulation of the Secreted Peptidyl-Prolyl Cis-Trans Isomerase A in Kidney Fibrosis. CELLS-BASEL 9(7): 1-23, doi: 10.3390/cells9071724
• Fang P, Ji Y, Silbern I, Doebele C, Ninov M, Lenz C, Oellerich T, Pan KT, Urlaub H (2020) A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics. NAT COMMUN 11(1): 5268, doi: 10.1038/s41467-020-19052-w
• Fish K, Comoglio F, Shaffer AL, Ji Y, Pan KT, Scheich S, Oellerich A, Doebele C, Ikeda M, Schaller SJ, Nguyen H, Muppidi J, Wright GW, Urlaub H, Serve H, Staudt LM, Longnecker R, Oellerich T (2020) Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A. P NATL ACAD SCI USA 117(42): 26318-26327, doi: 10.1073/pnas.2007946117
• Grapp M, Kaufmann C, Schwelm HM, Neukamm MA, Blaschke S, Eidizadeh A (2020) Intoxication cases associated with the novel designer drug 3',4'-methylenedioxy-α-pyrrolidinohexanophenone and studies on its human metabolism using high-resolution mass spectrometry. DRUG TEST ANAL 12(9): 1320-1335, doi: 10.1002/dta.2869
• Hamann F, Schmitt A, Favretto F, Hofele R, Neumann P, Xiang S, Urlaub H, Zweckstetter M, Ficner R (2020) Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. P NATL ACAD SCI USA 117(6): 2948-2956, doi: 10.1073/pnas.1907960117
• Hanses U, Kleinsorge M, Roos L, Yigit G, Li Y, Barbarics B, El-Battrawy I, Lan H, Tiburcy M, Hindmarsh R, Lenz C, Salinas G, Diecke S, Müller C, Adham I, Altmüller J, Nürnberg P, Paul T, Zimmermann WH, Hasenfuss G, Wollnik B, Cyganek L (2020) Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome-Associated Cardiomyopathy. CIRCULATION 142(11): 1059-1076, doi: 10.1161/CIRCULATIONAHA.119.044794
• Hellinger JW, Schömel F, Buse JV, Lenz C, Bauerschmitz G, Emons G, Gründker C (2020) Identification of drivers of breast cancer invasion by secretome analysis: insight into CTGF signaling. SCI REP-UK 10(1): 17889, doi: 10.1038/s41598-020-74838-8
• Kallner A, Petersmann A, Nauck M, Theodorsson E (2020) Measurement repeatability profiles of eight frequently requested measurands in clinical chemistry determined by duplicate measurements of patient samples. SCAND J CLIN LAB INV 80(3): 202-209, doi: 10.1080/00365513.2020.1716266
• Keutmann S, Zylla S, Dahl M, Friedrich N, Landgraf R, Heinemann L, Kallner A, Nauck M, Petersmann A (2020) Measurement Uncertainty Impacts Diagnosis of Diabetes Mellitus: Reliable Minimal Difference of Plasma Glucose Results. DIABETES THER 11(1): 293-303, doi: 10.1007/s13300-019-00740-w
• Königsmann T, Parfentev I, Urlaub H, Riedel D, Schuh R (2020) The bicistronic gene würmchen encodes two essential components for epithelial development in Drosophila. DEV BIOL 463(1): 53-62, doi: 10.1016/j.ydbio.2020.04.005
• Koziolek M, Mueller GA, Dihazi GH, Jung K, Altubar C, Wallbach M, Markovic I, Raddatz D, Jahn O, Karaköse H, Lenz C, Urlaub H, Dihazi A, El Meziane A, Dihazi H (2020) Urine E-cadherin: A Marker for Early Detection of Kidney Injury in Diabetic Patients. J CLIN MED 9(3): 1-21, doi: 10.3390/jcm9030639
• Kwiatkowski M, Asif AR, Schumacher J, Brenig B, Zischler H, Herlyn H (2020) Intra-Protein Coevolution Is Increasingly Functional with Greater Proximity to Fertilization. CYTOGENET GENOME RES 160(6): 295-308, doi: 10.1159/000509584
• Lavdovskaia E, Denks K, Nadler F, Steube E, Linden A, Urlaub H, Rodnina MV, Richter-Dennerlein R (2020) Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. NUCLEIC ACIDS RES 48(22): 12929-12942, doi: 10.1093/nar/gkaa1132
• Liess AKL, Kucerova A, Schweimer K, Schlesinger D, Dybkov O, Urlaub H, Mansfeld J, Lorenz S (2020) Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. SCI SIGNAL 13(654): 1-16, doi: 10.1126/scisignal. aba8208
• Linden A, Deckers M, Parfentev I, Pflanz R, Homberg B, Neumann P, Ficner R, Rehling P, Urlaub H (2020) A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria. MOL CELL PROTEOMICS 19(7): 1161-1178, doi: 10.1074/mcp. RA120.002028
• Menzel J, Kownatzki-Danger D, Tokar S, Ballone A, Unthan-Fechner K, Kilisch M, Lenz C, Urlaub H, Mori M, Ottmann C, Shattock MJ, Lehnart SE, Schwappach B (2020) 14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban. SCI SIGNAL 13(647): 43-48, doi: 10.1126/scisignal. aaz1436
• Müller M, James C, Lenz C, Urlaub H, Kehlenbach RH (2020) Probing the Environment of Emerin by Enhanced Ascorbate Peroxidase 2 (APEX2) -Mediated Proximity Labeling. CELLS-BASEL 9(3): 25-30, doi: 10.3390/cells9030605
• Netz E, Dijkstra TMH, Sachsenberg T, Zimmermann L, Walzer M, Monecke T, Ficner R, Dybkov O, Urlaub H, Kohlbacher O (2020) OpenPepXL: An Open-Source Tool for Sensitive Identification of Cross-Linked Peptides in XL-MS. MOL CELL PROTEOMICS 19(12): 2157-2168, doi: 10.1074/mcp. TIR120.002186
• Pan H, Steixner-Kumar AA, Seelbach A, Deutsch N, Ronnenberg A, Tapken D, von Ahsen N, Mitjans M, Worthmann H, Trippe R, Klein-Schmidt C, Schopf N, Rentzsch K, Begemann M, Wienands J, Stöcker W, Weissenborn K, Hollmann M, Nave KA, Lühder F, Ehrenreich H (2020) Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury. MOL PSYCHIATR -: -, doi: 10.1038/s41380-020-0672-1
• Parfentev I, Schilbach S, Cramer P, Urlaub H (2020) An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. J PROTEOMICS 220: 103754, doi: 10.1016/j.jprot.2020.103754
• Sadlonova M, Meyer T, Binder L, Wachter R, Edelmann F, Herrmann-Lingen C (2020) Higher galectin-3 levels are independently associated with lower anxiety in patients with risk factors for heart failure. BIOPSYCHOSOC MED 14: 24, doi: 10.1186/s13030-020-00195-7
• Schnelle M, Chong M, Zoccarato A, Elkenani M, Sawyer GJ, Hasenfuss G, Ludwig C, Shah AM (2020) In vivo [U-13 C] glucose labeling to assess heart metabolism in murine models of pressure and volume overload. AM J PHYSIOL-HEART C 319(2): H422-H431, doi: 10.1152/ajpheart.00219.2020
• Schulze S, Adams Z, Cerletti M, De Castro R, Ferreira-Cerca S, Fufezan C, Giménez MI, Hippler M, Jevtic Z, Knüppel R, Legerme G, Lenz C, Marchfelder A, Maupin-Furlow J, Paggi RA, Pfeiffer F, Poetsch A, Urlaub H, Pohlschroder M (2020) The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics. NAT COMMUN 11(1): 3145, doi: 10.1038/s41467-020-16784-7
• Singh K, Graf B, Linden A, Sautner V, Urlaub H, Tittmann K, Stark H, Chari A (2020) Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase. CELL 180(6): 1130-1143.e20, doi: 10.1016/j.cell.2020.02.034
• Stützer A, Welp LM, Raabe M, Sachsenberg T, Kappert C, Wulf A, Lau AM, David SS, Chernev A, Kramer K, Politis A, Kohlbacher O, Fischle W, Urlaub H (2020) Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry. NAT COMMUN 11(1): 5250, doi: 10.1038/s41467-020-19047-7
• Süße M, Reiber H, Grothe M, Petersmann A, Nauck M, Dressel A, Hannich MJ (2020) Free light chain kappa and the polyspecific immune response in MS and CIS - Application of the hyperbolic reference range for most reliable data interpretation. J NEUROIMMUNOL 346: 577287, doi: 10.1016/j.jneuroim.2020.577287
• Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will CL, Bertram K, Urlaub H, Kastner B, Stark H, Lührmann R (2020) Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. SCIENCE 370(6523): 1-13, doi: 10.1126/science.abc3753
• Ukmar-Godec T, Fang P, Ibáñez de Opakua A, Henneberg F, Godec A, Pan KT, Cima-Omori MS, Chari A, Mandelkow E, Urlaub H, Zweckstetter M (2020) Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. SCI ADV 6(30): eaba3916, doi: 10.1126/sciadv. aba3916
• Vahsen BF, Ribas VT, Sundermeyer J, Boecker A, Dambeck V, Lenz C, Shomroni O, Caldi Gomes L, Tatenhorst L, Barski E, Roser AE, Michel U, Urlaub H, Salinas G, Bähr M, Koch JC, Lingor P (2020) Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. CELL DEATH DIFFER 27(10): 2810-2827, doi: 10.1038/s41418-020-0543-y
• Volland C, Schott P, Didié M, Männer J, Unsöld B, Toischer K, Schmidt C, Urlaub H, Nickels K, Knöll R, Schmidt A, Guan K, Hasenfuß G, Seidler T (2020) Control of p21Cip by BRCA1-associated protein is critical for cardiomyocyte cell cycle progression and survival. CARDIOVASC RES 116(3): 592-604, doi: 10.1093/cvr/cvz177
• Vos SM, Farnung L, Linden A, Urlaub H, Cramer P (2020) Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. NAT STRUCT MOL BIOL 27(7): 668-677, doi: 10.1038/s41594-020-0437-1
• Wagner FR, Dienemann C, Wang H, Stützer A, Tegunov D, Urlaub H, Cramer P (2020) Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. NATURE 579(7799): 448-451, doi: 10.1038/s41586-020-2088-0
• Wang H, Dienemann C, Stützer A, Urlaub H, Cheung ACM, Cramer P (2020) Structure of the transcription coactivator SAGA. NATURE 577(7792): 717-720, doi: 10.1038/s41586-020-1933-5
• Wasser K, Weber-Krüger M, Gröschel S, Uphaus T, Liman J, Hamann GF, Kermer P, Seegers J, Binder L, Gelbrich G, Gröschel K, Wachter R (2020) Brain Natriuretic Peptide and Discovery of Atrial Fibrillation After Stroke: A Subanalysis of the Find-AFRANDOMISED Trial. STROKE 51(2): 395-401, doi: 10.1161/STROKEAHA.119.026496
• Yatsenko AS, Kucherenko MM, Xie Y, Aweida D, Urlaub H, Scheibe RJ, Cohen S, Shcherbata HR (2020) Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. BMC MED 18(1): 8, doi: 10.1186/s12916-019-1478-3
• Zhang Z, Will CL, Bertram K, Dybkov O, Hartmuth K, Agafonov DE, Hofele R, Urlaub H, Kastner B, Lührmann R, Stark H (2020) Molecular architecture of the human 17S U2 snRNP. NATURE 583(7815): 310-313, doi: 10.1038/s41586-020-2344-3

2018

• Aksu M, Pleiner T, Karaca S, Kappert C, Dehne HJ, Seibel K, Urlaub H, Bohnsack MT, Görlich D (2018) Xpo7 is a broad-spectrum exportin and a nuclear import receptor. J CELL BIOL 217(7): 2329-2340, doi: 10.1083/jcb.201712013
• Batschkus S, Cingoez G, Urlaub H, Miosge N, Kirschneck C, Meyer-Marcotty P, Lenz C (2018) A new albumin-depletion strategy improves proteomic research of gingival crevicular fluid from periodontitis patients. CLIN ORAL INVEST 22(3): 1375-1384, doi: 10.1007/s00784-017-2213-0
• Behler J, Sharma K, Reimann V, Wilde A, Urlaub H, Hess WR (2018) The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. NAT MICROBIOL 3(3): 367-377, doi: 10.1038/s41564-017-0103-5
• Blaschke M, Koepp R, Lenz C, Kruppa J, Jung K, Siggelkow H (2018) Crohn's disease patient serum changes protein expression in a human mesenchymal stem cell model in a linear relationship to patients' disease stage and to bone mineral density. J CLIN TRANS ENDOCRINOL 13: 26-38, doi: 10.1016/j.jcte.2018.06.002
• Bohnenberger H, Kaderali L, Ströbel P, Yepes D, Plessmann U, Dharia NV, Yao S, Heydt C, Merkelbach-Bruse S, Emmert A, Hoffmann J, Bodemeyer J, Reuter-Jessen K, Lois AM, Dröge LH, Baumeister P, Walz C, Biggemann L, Walter R, Häupl B, Comoglio F, Pan KT, Scheich S, Lenz C, Küffer S, Bremmer F, Kitz J, Sitte M, Beißbarth T, Hinterthaner M, Sebastian M, Lotz J, Schildhaus HU, Wolff H, Danner BC, Brandts C, Büttner R, Canis M, Stegmaier K, Serve H, Urlaub H, Oellerich T (2018) Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis. EMBO MOL MED 10(9): -, doi: 10.15252/emmm.201708428
• Braun J, Fischer S, Xu ZZ, Sun H, Ghoneim DH, Gimbel AT, Plessmann U, Urlaub H, Mathews DH, Weigand JE (2018) Identification of new high affinity targets for Roquin based on structural conservation. NUCLEIC ACIDS RES 46(22): 12109-12125, doi: 10.1093/nar/gky908
• Buddeweg A, Sharma K, Urlaub H, Schmitz RA (2018) sRNA41 affects ribosome binding sites within polycistronic mRNAs in Methanosarcina mazei Gö1. MOL MICROBIOL 107(5): 595-609, doi: 10.1111/mmi.13900
• Cheng S, Tereshchenko J, Zimmer V, Vachey G, Pythoud C, Rey M, Liefhebber J, Raina A, Streit F, Mazur A, Bähr M, Konstantinova P, Déglon N, Kügler S (2018) Therapeutic efficacy of regulable GDNF expression for Huntington's and Parkinson's disease by a high-induction, background-free "GeneSwitch" vector. EXP NEUROL 309: 79-90, doi: 10.1016/j.expneurol.2018.07.017
• Cyganek L, Tiburcy M, Sekeres K, Gerstenberg K, Bohnenberger H, Lenz C, Henze S, Stauske M, Salinas G, Zimmermann WH, Hasenfuss G, Guan K (2018) Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI INSIGHT 3(12): 1-10, doi: 10.1172/jci.insight.99941
• Dickmanns A, Zschiedrich CP, Arens J, Parfentev I, Gundlach J, Hofele R, Neumann P, Urlaub H, Görke B, Ficner R, Stülke J (2018) Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh in Bacillus subtilis. J BIOL CHEM 293(16): 5781-5792, doi: 10.1074/jbc. RA117.001289
• Dihazi H, Asif AR, Beißbarth T, Bohrer R, Feussner K, Feussner I, Jahn O, Lenz C, Majcherczyk A, Schmidt B, Schmitt K, Urlaub H, Valerius O (2018) Integrative omics - from data to biology. EXPERT REV PROTEOMIC 15(6): 463-466, doi: 10.1080/14789450.2018.1476143
• Eidizadeh A, Asif AR, von Ahsen N, Binder L, Schnelle M (2018) Differences in procalcitonin measurements between three BRAHMS-partnered immunoassays(Liaison, Elecsys and Architect). CLIN CHEM LAB MED 0: 1-4, doi: 10.1515/cclm-2018-0916
• Eidizadeh A, von Ahsen N, Friedewald S, Binder L (2018) Macro-CK type 2 in metastatic prostate cancer. DIAGNOSIS (Berl) 0: -, doi: 10.1515/dx-2018-0039
• Fangauf SV, Herbeck Belnap B, Meyer T, Albus C, Binder L, Deter HC, Ladwig KH, Michal M, Ronel J, Rothenberger A, Söllner W, Wachter R, Weber CS, Herrmann-Lingen C, SPIRR-CAD study group (2018) Associations of NT-proBNP and parameters of mental health in depressed coronary artery disease patients. PSYCHONEUROENDOCRINO 96: 188-194, doi: 10.1016/j.psyneuen.2018.06.001
• Fornasiero EF, Mandad S, Wildhagen H, Alevra M, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Sakib MS, Fard MK, Kirli K, Centeno TP, Vidal RO, Rahman RU, Benito E, Fischer A, Dennerlein S, Rehling P, Feussner I, Bonn S, Simons M, Urlaub H, Rizzoli SO (2018) Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. NAT COMMUN 9(1): 4230, doi: 10.1038/s41467-018-06519-0
• Grapp M, Kaufmann C, Streit F, Binder L (2018) Systematic forensic toxicological analysis by liquid-chromatography-quadrupole-time-of-flight mass spectrometry in serum and comparison to gas chromatography-mass spectrometry. FORENSIC SCI INT 287: 63-73, doi: 10.1016/j.forsciint.2018.03.039
• Haselbach D, Komarov I, Agafonov DE, Hartmuth K, Graf B, Dybkov O, Urlaub H, Kastner B, Lührmann R, Stark H (2018) Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex. CELL 172(3): 454-464.e11, doi: 10.1016/j.cell.2018.01.010
• Johannsson S, Neumann P, Wulf A, Welp LM, Gerber HD, Krull M, Diederichsen U, Urlaub H, Ficner R (2018) Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. SCI REP-UK 8(1): 8880, doi: 10.1038/s41598-018-27118-5
• Lavdovskaia E, Kolander E, Steube E, Mai MMQ, Urlaub H, Richter-Dennerlein R (2018) The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis. NUCLEIC ACIDS RES 46(16): 8471-8482, doi: 10.1093/nar/gky701
• Maier LK, Stachler AE, Brendel J, Stoll B, Fischer S, Haas KA, Schwarz TS, Alkhnbashi OS, Sharma K, Urlaub H, Backofen R, Gophna U, Marchfelder A (2018) The nuts and bolts of the Haloferax CRISPR-Cas system I-B. RNA BIOL -: 1-12, doi: 10.1080/15476286.2018.1460994
• Mandad S, Rahman RU, Centeno TP, Vidal RO, Wildhagen H, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Kirli K, Benito E, Fischer A, Yousefi RY, Dennerlein S, Rehling P, Feussner I, Urlaub H, Bonn S, Rizzoli SO, Fornasiero EF (2018) The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. SCI REP-UK 8(1): 16913, doi: 10.1038/s41598-018-35277-8
• Masanta WO, Zautner AE, Lugert R, Bohne W, Gross U, Leha A, Dakna M, Lenz C (2018) Proteome Profiling by Label-Free Mass Spectrometry Reveals Differentiated Response of Campylobacter jejuni 81-176 to Sublethal Concentrations of Bile Acids. PROTEOM CLIN APPL e1800083: e1800083, doi: 10.1002/prca.201800083
• Mühlhausen S, Schmitt HD, Pan KT, Plessmann U, Urlaub H, Hurst LD, Kollmar M (2018) Endogenous Stochastic Decoding of the CUG Codon by Competing Ser- and Leu-tRNAs in Ascoidea asiatica. CURR BIOL 28(13): 2046-2057.e5, doi: 10.1016/j.cub.2018.04.085
• Oroz J, Chang BJ, Wysoczanski P, Lee CT, Pérez-Lara Á, Chakraborty P, Hofele RV, Baker JD, Blair LJ, Biernat J, Urlaub H, Mandelkow E, Dickey CA, Zweckstetter M (2018) Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. NAT COMMUN 9(1): 4532, doi: 10.1038/s41467-018-06880-0
• Papathanasiou P, Erdmann S, Leon-Sobrino C, Sharma K, Urlaub H, Garrett RA, Peng X (2018) Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1. RNA BIOL -: 1-9, doi: 10.1080/15476286.2018.1511674
• Ramani A, Mariappan A, Gottardo M, Mandad S, Urlaub H, Avidor-Reiss T, Riparbelli M, Callaini G, Debec A, Feederle R, Gopalakrishnan J (2018) Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes. CELL REP 25(13): 3618-3630.e6, doi: 10.1016/j.celrep.2018.11.102
• Rieger H, Schmidt P, Schaeffeler E, Abe M, Schiffhauer M, Schwab M, von Ahsen N, Zurek G, Kirchherr H, Shipkova M, Wieland E (2018) Validation of a high-performance liquid chromatography method for thiopurine S-methyltransferase activity in whole blood using 6-mercaptopurine as substrate. CLIN CHEM LAB MED 56(5): 803-809, doi: 10.1515/cclm-2017-0670
• Schäffler H, Geiss D, Gittel N, Rohde S, Huth A, Glass Ä, Brandhorst G, Jaster R, Lamprecht G (2018) Mutations in the NOD2 gene are associated with a specific phenotype and lower anti-tumor necrosis factor trough levels in Crohn's disease. J DIGEST DIS 19(11): 678-684, doi: 10.1111/1751-2980.12677
• Sonnleitner E, Wulf A, Campagne S, Pei XY, Wolfinger MT, Forlani G, Prindl K, Abdou L, Resch A, Allain FHT, Luisi BF, Urlaub H, Bläsi U (2018) Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa. NUCLEIC ACIDS RES 46(3): 1470-1485, doi: 10.1093/nar/gkx1245
• Vogelgsang J, Shahpasand-Kroner H, Vogelgsang R, Streit F, Vukovich R, Wiltfang J (2018) Multiplex immunoassay measurement of amyloid-β42 to amyloid-β40 ratio in plasma discriminates between dementia due to Alzheimer's disease and dementia not due to Alzheimer's disease. EXP BRAIN RES 236(5): 1241-1250, doi: 10.1007/s00221-018-5210-x
• Vos SM, Farnung L, Boehning M, Wigge C, Linden A, Urlaub H, Cramer P (2018) Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. NATURE 560(7720): 607-612, doi: 10.1038/s41586-018-0440-4
• Vos SM, Farnung L, Urlaub H, Cramer P (2018) Structure of paused transcription complex Pol II-DSIF-NELF. NATURE 560(7720): 601-606, doi: 10.1038/s41586-018-0442-2